Summary
Marfan syndrome is a genetic disorder which impacts the body’s connective tissue. (Connective tissue is what pieces together all of your body’s different organs of sorts together, it also helps your body grow and develop correctly). Marfan syndrome is caused by a defect in the gene, FBN1. FBN1 teaches the body how to make fibrillin-1. Fibrillin-1 is a large extracellular matrix glycoprotein. ( Extracellular matrix glycoproteins are proteins that live on the membrane of a cell, that collect signals, then tell the cell what to do. ) it’s used as a component of 10-12 nm calcium-binding microfibrils.